Raising the Standard for Myasthenia Gravis Care
 

Release Date: April 28, 2025

Expiration Date:  April 28, 2026

 
STATEMENT OF NEED 

Generalized myasthenia gravis (gMG) presents with complex diagnostic and therapeutic challenges due to its heterogeneous presentation, risk of rapid progression, and evolving treatment landscape. Delayed diagnosis, underrecognition of refractory disease, and inconsistent use of new targeted therapies contribute to ongoing patient morbidity. While novel agents such as complement and FcRn inhibitors offer more precise and tolerable options compared to traditional immunosuppressants, their integration into practice remains limited due to outdated guidelines and clinical uncertainty. This curriculum addresses these gaps by equipping clinicians with the knowledge and tools to identify high-risk patients early, evaluate and apply emerging therapies, and implement individualized treatment strategies through a structured, case-based, and peer-driven learning model. 

 
EDUCATIONAL OBJECTIVES

1. IDENTIFY patients at risk for severe or recalcitrant Myasthenia Gravis
2. APPRAISE safety and efficacy data for new and emerging treatment options for Myasthenia Gravis
3. EVALUATE patient response to standard treatment to develop individualized care plans
4. DIFFERENTIATE patients who would benefit from more targeted therapies at early stages or after developing refractory disease

 
TARGET AUDIENCE 

General Neurologists, Neuromuscular Specialists, Specialty & General NPs & PAs

FACULTY 

Dr. Joshua P. Alpers, MD Neurologist; Director, Certified Electrodiagnostic Laboratory  Erlanger Neurology/Erlanger Medical Center  Chattanooga, TN

DISCLOSURE OF FINANCIAL RELATIONSHIPS 
The “Policy on Identification, Mitigation, and Disclosure of Relevant Financial Relationships” of Albert Einstein College of Medicine-Montefiore Medical Center requires that any individual in control of content, including faculty, participating in CME activities disclose to the audience all relevant financial relationships with ineligible companies* in the past 24 months. Any individual in control of content who refuses to disclose, or whose disclosed relationships prove to create a conflict of interest, will be recused. 
 
Individuals with the absence of relevant financial relationships with ineligible companies will be disclosed to the audience.

All financial relationships of individuals in a position to control the content of this CME activity are identified and mitigated prior to the educational activity. 

*The ACCME defines an ineligible company as those whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. 
 
ACCREDITED PROVIDER DISCLOSURE 
The planners, and the Albert Einstein College of Medicine-Montefiore Medical Center staff for this educational activity have disclosed no relevant financial relationship(s) with an ACCME-defined ineligible company in the last 24 months.

Faculty Disclosure(s) 

David Kaufman, MD has no relevant financial relationships with ineligible companies.

Joshua Alpers, MD has disclosed the following financial relationships: Consultant: Alexion Pharmaceuticals, Argenx, CSL Behring, UCB.

PROVIDERSHIP
This educational activity is jointly provided by Albert Einstein College of Medicine-Montefiore Medical Center and RealCME. 

 
ACCREDITATION STATEMENT 

In support of improving patient care, this activity has been planned and implemented by Albert Einstein College of Medicine-Montefiore Medical Center and RealCME, LLC. Albert Einstein College of Medicine-Montefiore Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. 
 
CREDIT DESIGNATION STATEMENT 
Albert Einstein College of Medicine-Montefiore Medical Center designates this other activity (blended live and enduring curriculum) for a maximum of 4.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 
 

Other Credits

American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Nurse Practitioners National Certification Program accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society. Physician assistants may receive a maximum of 4.75 hours of Category 1 credit for completing this program.


American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) Program

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 4.75 Medical Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
 

DISCLOSURE OF UNLABELED USE 
This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a clinician relative to diagnostic and treatment options for a specific patient’s medical condition.

DISCLAIMER
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Albert Einstein College of Medicine-Montefiore Medical Center, RealCME or Jazz Pharmaceuticals. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. 
 

METHOD OF PARTICIPATION/INSTRUCTIONS ON HOW TO RECEIVE CREDIT

Estimated time to complete this activity: 4 hours and 45 minutes.
 
To obtain credit, a score of 70% or better on the Final Assessment is required. This activity is offered at no cost to participants. Please proceed with the activity until you have successfully completed this curriculum, answered all test questions, completed the Final Assessment, Post Group Assessment, and evaluation, and have received a digital copy of your credit certificate.

• Baseline/Final Assessments: 30 minutes each for a total of up to 1.00 hour of CME 
• Three (3) Self-Study Modules: 15 minutes each for a total of up to 0.75 hour of CME 
• Two (2) Live Group Discussions: 45 minutes each for a total of up to 1.50 hour of CME 
• Two Group Challenges (2): 30 minutes each for a total of up to 1.00 hour of CME 
• Action Plan (1) development: 30 minutes for a total of up to 0.50 hour of CME 

If you are seeking credit, you must complete the assessment and evaluation at the conclusion of the activity. Your certificate can be printed immediately. 
 
PRIVACY STATEMENT 
Albert Einstein College of Medicine-Montefiore Medical Center, Center for Continuing Professional Development (Einstein-Montefiore) protects the privacy of personal and other information regarding participants and education collaborators. Einstein-Montefiore will not release personally identifiable information to a third party without the individual’s consent, except such information as is required for reporting to the ACCME. Einstein-Montefiore maintains physical, electronic, and procedural safeguards that comply with federal regulations to protect against the loss, misuse, or alteration of information collected from you. 
 
COLLECTION AND USE OF YOUR PERSONAL INFORMATION 
The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing an activity. Required items include first name, last name, middle initial, degree, email address, address, and phone number. These items are necessary. Participants are also required to complete an evaluation of each activity. All evaluative information submitted is collected, retained, and used by Einstein-Montefiore to continuously improve the learning experience. Einstein-Montefiore will not transfer, sell, or share personal information with outside parties or otherwise disclose personal information unless required to in a legal process. Einstein-Montefiore will retain your personal data only for the period necessary to accomplish the stated purposes and to comply with applicable laws. 

CONTACT INFORMATION
For questions regarding CME credit, contact Albert Einstein College of Medicine-Montefiore Medical Center at cme@montefiore.org.
 
For technical questions related to this activity, please contact support@gathered.com.

ACKNOWLEDGEMENT OF FINANCIAL SUPPORT

This activity is supported by an educational grant from Argenx US Inc.