TITLE
New Pathways in Narcolepsy Treatment

PROGRAM PARTNERS
This activity is jointly provided by Albert Einstein College of Medicine-Montefiore Medical, the Narcolepsy Network and RealCME
ACKNOWLEDGEMENT OF FINANCIAL SUPPORT
This activity is supported by an educational grant from Takeda
Release Date: January 5, 2026
Expiration Date: January 5, 2027
STATEMENT OF NEED
Given the ongoing challenges in diagnosis and management, along with evolving criteria and new treatment options, education for sleep medicine specialists is critical. The proposed curriculum will foster expert-guided, small-group discussions and collaborative learning to help clinicians optimize therapy selection, prepare for integration of novel treatments, and improve patient-centered care. Although orexin agonists are not yet FDA approved, offering clinicians a structured opportunity to review emerging data, share practical insights, and discuss implementation strategies represents a timely and impactful opportunity to advance narcolepsy care.
EDUCATIONAL OBJECTIVES
DIFFERENTIATE between NT1 and NT2 based on clinical presentation, diagnostic testing, and biomarker data
EXPLAIN the role of orexin in sleep-wake regulation and its relevance to the pathophysiology of NT1
EVALUATE the current standard of care for narcolepsy, including the indications and limitations of approved therapies
ASSESS emerging therapeutic strategies and their potential integration into future treatment algorithms
TARGET AUDIENCE
This activity is designed for Sleep Medicine specialists, including physicians, fellows, and other clinicians involved in the diagnosis, management, and treatment of sleep disorders. It may also be of interest to neurologists, pulmonologists, primary care providers, and other healthcare professionals who collaborate in the care of patients with sleep-related conditions.
FACULTY
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David Plante, MD, PhD Associate Professor of Psychiatry, University of Wisconsin-Madison Medical Director, Wisconsin Institute for Sleep and Consciousness
Dr. David T. Plante, MD, PhD, is an Associate Professor of Psychiatry at the University of Wisconsin-Madison. He also serves as the Medical Director of the Wisconsin Institute for Sleep and Consciousness. Dr. Plante received his medical degree from the University of North Carolina School of Medicine. He completed his residency in Adult Psychiatry at Massachusetts General Hospital/McLean Hospital and a fellowship in Sleep Medicine at Brigham and Women's Hospital in Boston, MA. Dr. Plante is board certified in both psychiatry and sleep medicine. His research focuses on the pathophysiology and evaluation of disorders of central hypersomnolence, particularly hypersomnolence comorbid with affective illness. He is involved in various aspects of sleep medicine, including treatment for conditions like narcolepsy, sleep apnea, insomnia, and circadian rhythm disorders. |
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Disclosure(s): |
David Plante, MD, PhD, has the following relevant financial relationship with ACCME-defined ineligible companies within the past 24 months: Consultant/Advisor Board for: Alkermes, Inc; Centessa, Inc; Harmony Biosciences, LLC; Jazz Pharmaceuticals, Inc. and Takeda. Advisory Board: Apnimed, Inc. The relationship with Apnimed, Inc has ended. Jazz, Alkermes, Harmony Biosciences, Apnimed, Centessa, Takeda business lines and/or products is relevant to your presentation, |
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Karin G. Johnson, MD, FAAN, FAASM Professor of Neurology; Vice Chair for Academic Affairs UMass Chan Medical School-Baystate
Karin G. Johnson, MD, FAAN, FAASM, is a Professor of Neurology at the UMass Chan Medical School–Baystate, where she serves as Vice Chair for Academic Affairs and Medical Director of the Baystate Health Regional Sleep Program. She is Sleep Section Chair for the American Academy of Neurology and has national advocacy roles as Vice President of Save Standard Time and Co-Chair of the Coalition for Permanent Standard Time. Dr. Johnson’s clinical and scholarly work centers on sleep health and central nervous system disorders, with a focus on how circadian alignment affects neurologic outcomes.
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Disclosure(s): |
Karin G. Johnson, MD, FAAN, FAASM, has the following relevant financial relationship with ACCME-defined ineligible companies within the past 24 months. : She served as the Site Principal Investigator for Apnimed, Inc., and her institution received research support from Apnimed, Inc. |
CONTENT REVIEWER
Kristina Maselli, MD
Assistant Professor of Neurology
Associate Program Director, Sleep Medicine Fellowship
Montefiore Headache Center
Montefiore Sleep Wake Disorders Center
Bronx, NY
Kristina Maselli, MD has no relevant financial relationships with ACCME-defined ineligible companies during the past 24 months.
PLANNERS
Steven Haimowitz, MD
RealCME
Steven Haimowitz, MD, has no relevant financial relationships with ACCME-defined ineligible companies during the past 24 months.
Erin Ash, MD
RealCME
Erin Ash, MD, has no relevant financial relationships with ACCME-defined ineligible companies during the past 24 months.
DISCLOSURE OF FINANCIAL RELATIONSHIPS
The “Policy on Identification, Mitigation, and Disclosure of Relevant Financial Relationships” of Albert Einstein College of Medicine-Montefiore Medical Center requires that any individual in control of content, including faculty, participating in CME activities disclose to the audience all relevant financial relationships with ineligible companies* in the past 24 months. Any individual in control of content who refuses to disclose, or whose disclosed relationships prove to create a conflict of interest, will be recused.
Individuals with the absence of relevant financial relationships with ineligible companies will be disclosed to the audience.
All financial relationships of individuals in a position to control the content of this CME activity are identified and mitigated prior to the educational activity.
*The ACCME defines an ineligible company as those whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.
PROVIDERSHIP
This educational activity is jointly provided by Albert Einstein College of Medicine-Montefiore Medical Center, the Narcolepsy Network and RealCME.
ACCREDITATION STATEMENT

In support of improving patient care, this activity has been planned and implemented by Albert Einstein College of Medicine-Montefiore Medical Center and RealCME, LLC. Albert Einstein College of Medicine-Montefiore Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
CREDIT DESIGNATION STATEMENT
Albert Einstein College of Medicine-Montefiore Medical Center designates this other/blended activity for a maximum of 4.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Other Credits
American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.
American Academy of Nurse Practitioners National Certification Program accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.
American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society. Physician assistants may receive a maximum of 4.75 AMA PRA Category 1 Credits™ for completing this program.

American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) Program
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 4.75 Medical Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
DISCLOSURE OF UNLABELED USE
This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a clinician relative to diagnostic and treatment options for a specific patient’s medical condition.
DISCLAIMER
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Albert Einstein College of Medicine-Montefiore Medical Center, RealCME, and Takeda. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
METHOD OF PARTICIPATION/INSTRUCTIONS ON HOW TO RECEIVE CREDIT
Estimated time to complete this activity: 4.75 hours
To obtain credit, a score of 70% or better on the Final Assessment is required. This activity is offered at no cost to participants. Please proceed with the activity until you have successfully completed this curriculum, answered all test questions, completed the Final Assessment, Post Group Assessment, and evaluation, and have received a digital copy of your credit certificate.
If you are seeking credit, you must complete the assessment and evaluation at the conclusion of the activity. Your certificate can be printed immediately.
PRIVACY STATEMENT
Albert Einstein College of Medicine-Montefiore Medical Center, Center for Continuing Professional Development (Einstein-Montefiore) protects the privacy of personal and other information regarding participants and education collaborators. Einstein-Montefiore will not release personally identifiable information to a third party without the individual’s consent, except such information as is required for reporting to the ACCME. Einstein-Montefiore maintains physical, electronic, and procedural safeguards that comply with federal regulations to protect against the loss, misuse, or alteration of information collected from you.
COLLECTION AND USE OF YOUR PERSONAL INFORMATION
The submission of certain personally identifiable information is necessary to award and track the credits participants may earn after completing an activity. Required items include first name, last name, middle initial, degree, email address, address and phone number. These items are necessary. Participants are also required to complete an evaluation of each activity. All evaluative information submitted is collected, retained, and used by Einstein-Montefiore to continuously improve the learning experience. Einstein-Montefiore will not transfer, sell, or share personal information with outside parties or otherwise disclose personal information unless required to in a legal process. Einstein-Montefiore will retain your personal data only for the period necessary to accomplish the stated purposes and to comply with applicable laws.
CONTACT INFORMATION
For questions regarding CME credit, contact Albert Einstein College of Medicine-Montefiore Medical Center at cme@montefiore.org.
For technical questions related to this activity, please contact support@gathered.com.