Module 4 - The Role of Antibody-Drug Conjugates in the Treatment of HR+/HER2- Breast Cancer (7 minute video)

This module will examine the mechanisms, clinical benefits, and safety of ADCs, along with emerging data that highlight their potential in addressing resistance to endocrine and chemotherapy.

Sara M. Tolaney, MD, MPH

Chief, Division of Breast Oncology, Susan F. Smith Center for Women's Cancers
Associate Director, Susan F. Smith Center for Women's Cancers
Associate Professor of Medicine, Dana Farber Cancer Institute

Dr. Tolaney received her undergraduate degree from Princeton University in 1998 and her medical degree from UC San Francisco in 2002. She subsequently completed her residency in Internal Medicine at Johns Hopkins University, and fellowships in hematology and medical oncology at Dana-Farber Cancer Institute. She obtained a Masters in Public Health from the Harvard School of Public Health in 2007. In 2008, she joined the staff of Dana-Farber Cancer Institute and Brigham and Women's Hospital, where she serves as Chief of the Division of Breast Oncology.  She is a breast medical oncologist whose research focuses on the development of novel therapies in the treatment of breast cancer.  She has been instrumental in developing several treatment approaches for breast cancer, including approaches focused on tailoring therapy for early stage HER2+ disease, use of CDK 4/6 inhibitors, antibody drug conjugates, and immunotherapy.

1.
APPLY data from recent clinical trials using ADCs in the treatment of TNBC to sequencing strategies in patient care